The Nobel Prize in Chemistry 2009 : Ribosomes In The Spotlight
The Nobel Prize in Chemistry has been awarded to two Americans and one Israeli for their work on ribosomes. This research promises advances in the treatment of diseases through the improvement of antibiotics.

The Nobel chemistry prize three researchers for their studies of ribosomes: Venkatraman Ramakrishnan (MRC Laboratory of Molecular Biology, Cambridge, United Kingdom), Thomas A. Steitz (Yale University, USA) and Ada E. Yonath (Weizmann Institute of Science, Israel).

These components of the cell, real manufacturing proteins via translation of DNA, are major targets for antibiotic action of many of them being to prevent bacterial ribosomes to function, said the academy Royal Swedish Society of Sciences.

Together, they conducted a three-dimensional mapping at the scale of the atom in this complex enzyme. Ribosomes, real biochemical plants, read the genetic code to produce proteins necessary for the establishment and functioning of organisms. Hemoglobin, hormone, enzyme digestion, consisting of cells, antibodies ... all that is synthesized by ribosomes. This is true for humans, but also for disease-causing bacteria.

In blocking the functioning of the ribosomes that antibiotics fight against bacteria. Better understanding is therefore better to fight against the disease.

The three distinguished scientists have used the X-ray crystallography to detail the atomic structure of ribosomes and develop models to explain their association with various antibiotics. These models are now used for the development of new drugs.

With the 10 million kronor (980,000 euros), the Nobel chemistry prize investment of all the teams of these three researchers, whose work is used since 2000 to develop new antibiotics.


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