Ibuprofen, Aspirin, Naproxen Effective at Reducing Risk of Alzheimer’s Disease Different types of drugs non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, and aspirin, appear to be equally relevant in reducing the risk of Alzheimer's disease, according to the largest study of its kind published in May 28, 2008, online Neurology ®, the medical journal of the American Academy of Neurology. Experts have debated whether a certain group of NSAIDs that includes ibuprofen may be more beneficial than another group that includes naproxen and aspirin information. Using Six Different studies, the data reviewed by researchers on the use of NSAIDs in 13,499 people without dementia. Over the course of these six studies, 820 participants developed Alzheimer's disease.
Researchers found that people who used NSAIDs had risk 23 percent less to develop Alzheimer's disease compared to those who never used NSAIDs. The risk reduction did not appear to depend on the type of NSAID taken.
"It is an interesting finding because it seems to challenge a current theory that the NSAID group which includes ibuprofen may work better in reducing the risk of Alzheimer's person," said lead author Peter P. Zandi, PhD study, with the school at Johns Hopkins Bloomberg Public Health in Baltimore, MD. "We thought that the NSAID group which includes ibuprofen to target a type of plaque in the brain found in Alzheimer's patients. But our results suggest it may have their other reasons for these drugs which can reduce the risk of Alzheimer's."
The author Chris Szekely, PhD wire out of the review with the medical centre, Cedars Sinai in Los Angeles, said the discrepancy between studies such as this one and the negative clinical trials of NSAIDs in the treatment or prevention of Alzheimer's need to be explored further.
Researchers found that people who used NSAIDs had risk 23 percent less to develop Alzheimer's disease compared to those who never used NSAIDs. The risk reduction did not appear to depend on the type of NSAID taken.
"It is an interesting finding because it seems to challenge a current theory that the NSAID group which includes ibuprofen may work better in reducing the risk of Alzheimer's person," said lead author Peter P. Zandi, PhD study, with the school at Johns Hopkins Bloomberg Public Health in Baltimore, MD. "We thought that the NSAID group which includes ibuprofen to target a type of plaque in the brain found in Alzheimer's patients. But our results suggest it may have their other reasons for these drugs which can reduce the risk of Alzheimer's."
The author Chris Szekely, PhD wire out of the review with the medical centre, Cedars Sinai in Los Angeles, said the discrepancy between studies such as this one and the negative clinical trials of NSAIDs in the treatment or prevention of Alzheimer's need to be explored further.
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