The p53 Gene Provide Protection Against Cancer
Genetic Scientists claim to have discovered a missing link which explains how a cell works to defend against cancer. This would be the p53 gene with the capacity to block or not the development of cancerous tumors. This discovery is a good step in the treatment and diagnosis of cancer.

This research has just been published in "Genes and Development" and was conducted by scientists in Singapore and the University of Dundee in Scotland.

The p53 gene was found there a little over 30 years and plays a crucial role in maintaining our body, ordering the damaged cells to "commit suicide" or stop dividing, thus stopping the spread of a cell potentially cancerous. In more than half of all cancers, this gene is damaged or inactive, leaving the path wide open for the development of cancerous cells.

In the latest research, scientists used a genetic turn to turn green zebra fish with their p53 gene was active. What researchers found is that in addition to creating the protein p53, the p53 gene produces a protein isoform that acts as switches as alternative and complementary to the p53 protein.

The zebrafish shares the p53 gene with the human

Normally, the zebra fish can survive with low doses of radiation since the presence of active p53 gene stops the multiplication of cells whose DNA is damaged. What scientists have observed is that the zebra fish without "switch alternative" died as a result of exposure to radiation.

This breakthrough in the fight against cancer is very important because understanding how cells react when in the presence of cancer cells is crucial. It is clear that the p53 gene plays an important role in controlling cancer development.

Source: BBC News


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